MONITORING AND ROBUST ADAPTIVE CONTROL OF FED-BATCH CULTURES OF MICROORGANISMS EXHIBITING OVERFLOW METABOLISM [ABSTRACT]

Monitoring and robust adaptive control of fed-batch cultures of microorganisms exhibiting overflow metabolism [abstract]

Overflow metabolism characterizes cells strains that are likely to produce inhibiting by-products resulting from an excess of substrate feeding and a saturated SUNSCREEN respiratory capacity.The critical substrate level separating the two different metabolic pathways is generally not well defined.Monitoring of this kind of cultures, going from mode

read more

Thai Adolescent Depression: Recurrence Prevention in Practice

This article aims to review the current practice of recurrence prevention and intervention of adolescent depressive disorder in Thailand.In particular, we assess the Clinical Practice Guideline of Major Depressive Disorder for General Practitioners (CPG-MDD-GP) for Thailand, which is now the official guideline for all depressive patients who are ch

read more


The Balanced Opioid Initiative: protocol for a clustered, sequential, multiple-assignment randomized trial to construct an adaptive implementation strategy to improve guideline-concordant opioid prescribing in primary care

Abstract Background Rates of Eye Serum opioid prescribing tripled in the USA between 1999 and 2015 and were associated with significant increases in opioid misuse and overdose death.Roughly half of all opioids are prescribed in primary care.Although clinical guidelines describe recommended opioid prescribing practices, implementing these guidelines

read more

Mix design optimization of concrete containing fly ash and slag for global warming potential and cost reduction

Mix design optimization is challenging because the properties of concrete depend on both the chemical and physical properties of the components and their relative proportions.In this paper a mix design optimization approach based on the application Toast Tongs of artificial intelligence, genetic algorithm optimisation, life-cycle assessment to quan

read more